Publications – Functional Genomics Laboratory

2017
Orozco-Solis R, Montellier E, Aguilar-Arnal L, Sato S, Vawter MP, Bunney BG, Bunney WE, Sassone-Corsi P. A Circadian Genomic Signature Common to Ketamine and Sleep Deprivation in the Anterior Cingulate Cortex. Biol Psychiatry. 2017 Sep 1;82(5):351-360
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Mittal K, Gonçalves VF, Harripaul R, Cuperfain AB, Rollins B, Tiwari AK, Zai CC, Maciukiewicz M, Müller DJ, Vawter MP, Kennedy JL. A comprehensive analysis of mitochondrial genes variants and their association with antipsychotic-induced weight gain. Schizophr Res. 2017 Sep;187:67-73
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Ramaker RC, Bowling KM, Lasseigne BN, Hagenauer MH, Hardigan AA, Davis NS, Gertz J, Cartagena PM, Walsh DM, Vawter MP, Jones EG, Schatzberg AF, Barchas JD, Watson SJ, Bunney BG, Akil H, Bunney WE, Li JZ, Cooper SJ, Myers RM. Post-mortem molecular profiling of three psychiatric disorders. Genome Med. 2017 Jul 28;9(1):72
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2016
Sellgren CM, Kegel ME, Bergen SE, Ekman CJ, Olsson S, Larsson M, Vawter MP, Backlund L, Sullivan PF, Sklar P, Smoller JW, Magnusson PK, Hultman CM, Walther-Jallow L, Svensson CI, Lichtenstein P, Schalling M, Engberg G, Erhardt S, Landén M. A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder. Mol Psychiatry. 2016 Oct;21(10):1342-50.
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Limon A, Mamdani F, Hjelm BE, Vawter MP, Sequeira A. Targets of polyamine dysregulation in major depression and suicide: Activity-dependent feedback, excitability, and neurotransmission. Neurosci Biobehav Rev. 2016 Jul;66:80-91
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Schneider K, Valdez J, Nguyen J, Vawter M, Galke B, Kurtz TW, Chan JY. Increased Energy Expenditure, Ucp1 Expression, and Resistance to Diet-induced Obesity in Mice Lacking Nuclear Factor-Erythroid-2-related Transcription Factor-2 (Nrf2). J Biol Chem. 2016 Apr 1;291(14):7754-66
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Morgan LZ, Rollins B, Sequeira A, Byerley W, DeLisi LE, Schatzberg AF, Barchas JD, Myers RM, Watson SJ, Akil H, Bunney WE, Vawter MP. Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders. Microarrays (Basel). 2016 Mar 7;5(1)
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2015
Hjelm BE, Rollins B, Mamdani F, Lauterborn JC, Kirov G, Lynch G, Gall CM, Sequeira A, Vawter MP. Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia. Mol Neuropsychiatry. 2015 Dec;1(4):201-19. doi: 10.1159/000441252. Epub 2015 Oct 28. Review. Erratum in: Mol Neuropsychiatry. 2016 May;2(1):60
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Mamdani F, Rollins B, Morgan L, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Potkin SG, Bunney WE, Vawter MP, Sequeira PA. Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder. Transl Psychiatry. 2015 Sep 15;5:e636
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Martin MV, Mirnics K, Nisenbaum LK, Vawter MP. Olanzapine Reversed Brain Gene Expression Changes Induced by Phencyclidine Treatment in Non-Human Primates. Mol Neuropsychiatry. 2015 Jul;1(2):82-93
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Sequeira A, Rollins B, Magnan C, van Oven M, Baldi P, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Bunney WE, Vawter MP. Mitochondrial mutations in subjects with psychiatric disorders. PLoS One. 2015 May 26;10(5):e0127280
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2014
Bunney BG, Li JZ, Walsh DM, Stein R, Vawter MP, Cartagena P, Barchas JD, Schatzberg AF, Myers RM, Watson SJ, Akil H, Bunney WE. Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder. Mol Psychiatry. 2014 Nov 4
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Mamdani F, Rollins B, Morgan L, Sequeira PA, Vawter MP. The somatic common deletion in mitochondrial DNA is decreased in schizophrenia. Schizophr Res. 2014 Nov;159(2-3):370-5.
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Cristina Kenney M, Chwa M, Atilano SR, Falatoonzadeh P, Ramirez C, Malik D, Tarek M, Cáceres-del-Carpio J, Nesburn AB, Boyer DS, Kuppermann BD, Vawter M,Jazwinski SM, Miceli M, Wallace DC, Udar N. Inherited mitochondrial DNA variants can affect complement, inflammation and apoptosis pathways: insights into mitochondrial-nuclear interactions. Hum Mol Genet. 2014 Jul 1;23(13):3537-51.
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Nurnberger JI Jr, Koller DL, Jung J, Edenberg HJ, Foroud T, Guella I, Vawter MP, Kelsoe JR; Psychiatric Genomics Consortium Bipolar Group. Identification of pathways for bipolar disorder: a meta-analysis. JAMA Psychiatry. 2014 Jun;71(6):657-64.
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van Erp TG, Guella I, Vawter MP, Turner J, Brown GG, McCarthy G, Greve DN, Glover GH, Calhoun VD, Lim KO, Bustillo JR, Belger A, Ford JM, Mathalon DH, Diaz M, Preda A, Nguyen D, Macciardi F, Potkin SG. Schizophrenia miR-137 locus risk genotype is associated with dorsolateral prefrontal cortex hyperactivation. Biol Psychiatry. 2014 Mar 1;75(5):398-405.
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Esmailpour T, Riazifar H, Liu L, Donkervoort S, Huang VH, Madaan S, Shoucri BM, Busch A, Wu J, Towbin A, Chadwick RB, Sequeira A, Vawter MP, Sun G, Johnston JJ, Biesecker LG, Kawaguchi R, Sun H, Kimonis V, Huang T. A splice donor mutation in NAA10 results in the dysregulation of the retinoic acid signalling pathway and causes Lenz microphthalmia syndrome. J Med Genet. 2014 Mar;51(3):185-96.
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Lavebratt C, Olsson S, Backlund L, Frisén L, Sellgren C, Priebe L, Nikamo P, Träskman-Bendz L, Cichon S, Vawter MP, Osby U, Engberg G, Landén M, Erhardt S, Schalling M. The KMO allele encoding Arg(452) is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression. Mol Psychiatry. 2014 Mar;19(3):334-41.
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Guella I, Vawter MP. Allelic imbalance associated with the schizophrenia risk SNP rs1344706 indicates a cis-acting variant in ZNF804A. Schizophr Res. 2014 Mar;153(1-3):243-5.
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Kenney MC, Chwa M, Atilano SR, Falatoonzadeh P, Ramirez C, Malik D, Tarek M, Del Carpio JC, Nesburn AB, Boyer DS, Kuppermann BD, Vawter MP, Jazwinski SM, Miceli MV, Wallace DC, Udar N. Molecular and bioenergetic differences between cells with African versus European inherited mitochondrial DNA haplogroups: implications for population susceptibility to diseases. Biochim Biophys Acta. 2014 Feb;1842(2):208-19.
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Guella I, Sequeira A, Rollins B, Morgan L, Myers RM, Watson SJ, Akil H, Bunney WE, Delisi LE, Byerley W, Vawter MP. Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex. Schizophr Res. 2014 Jan;152(1):111-6.
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2013
Hayashi-Takagi A, Vawter MP, Iwamoto K. Peripheral Biomarkers Revisited: Integrative Profiling of Peripheral Samples for Psychiatric Research. Biol Psychiatry. 2013 Oct 18.
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Tomita H, Ziegler ME, Kim HB, Evans SJ, Choudary PV, Li JZ, Meng F, Dai M, Myers RM, Neal CR, Speed TP, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Jones EG, Bunney WE, Vawter MP. G protein-linked signaling pathways in bipolar and major depressive disorders. Front Genet. 2013 Dec 23
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Mamdani F, Martin MV, Lencz T, Rollins B, Robinson DG, Moon EA, Malhotra AK, Vawter MP. Coding and Noncoding Gene Expression Biomarkers in Mood Disorders and Schizophrenia. Volume 35 (2013), Issue 1, Pages 11-21.
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Bharadwaj R, Jiang Y, Mao W, Jakovcevski M, Dincer A, Krueger W, Garbett K, Whittle C, Tushir JS, Liu J, Sequeira A, Vawter MP, Gardner PD, Casaccia P, Rasmussen T, Bunney WE Jr, Mirnics K, Futai K, Akbarian S. Conserved Chromosome 2q31 Conformations Are Associated with Transcriptional Regulation of GAD1 GABA Synthesis Enzyme and Altered in Prefrontal Cortex of Subjects with Schizophrenia. J Neurosci. 2013 Jul 17;33(29):11839-11851.
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Guella I, Sequeira A, Rollins B, Morgan L, Torri F, van Erp TG, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Bunney WE, Potkin SG, Macciardi F, Vawter MP. Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex. J Psychiatr Res. 2013 Sep;47(9):1215-21.
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Li JZ, Bunney BG, Meng F, Hagenauer MH, Walsh DM, Vawter MP, Evans SJ, Choudary PV, Cartagena P, Barchas JD, Schatzberg AF, Jones EG, Myers RM, Watson SJ Jr, Akil H, Bunney WE. Circadian patterns of gene expression in the human brain and disruption in major depressive disorder. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9950-5.
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Guffanti G, Torri F, Rasmussen J, Clark AP, Lakatos A, Turner JA, Fallon JH, Saykin AJ, Weiner M; ADNI the Alzheimer’s Disease Neuroimaging Initiative, Vawter MP, Knowles JA, Potkin SG, Macciardi F. Increased CNV-Region deletions in mild cognitive impairment (MCI) and Alzheimer’s disease (AD) subjects in the ADNI sample. Genomics. 2013 Apr 11. S0888-7543(13)00066-9.
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2012
Hawrylycz MJ, Lein ES, Guillozet-Bongaarts AL, Shen EH, Ng L, Miller JA, van de Lagemaat LN, Smith KA, Ebbert A, Riley ZL, Abajian C, Beckmann CF, Bernard A, Bertagnolli D, Boe AF, Cartagena PM, Chakravarty MM, Chapin M, Chong J, Dalley RA, Daly BD, Dang C, Datta S, Dee N, Dolbeare TA, Faber V, Feng D, Fowler DR, Goldy J, Gregor BW, Haradon Z, Haynor DR, Hohmann JG, Horvath S, Howard RE, Jeromin A, Jochim JM, Kinnunen M, Lau C, Lazarz ET, Lee C, Lemon TA, Li L, Li Y, Morris JA, Overly CC, Parker PD, Parry SE, Reding M, Royall JJ, Schulkin J, Sequeira PA, Slaughterbeck CR, Smith SC, Sodt AJ, Sunkin SM, Swanson BE, Vawter MP, Williams D, Wohnoutka P, Zielke HR, Geschwind DH, Hof PR, Smith SM, Koch C, Grant SG, Jones AR. An anatomically comprehensive atlas of the adult human brain transcriptome. Nature. 2012 Sep 20;489(7416):391-9.
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Backlund L, Lavebratt C, Frisén L, Nikamo P, Hukic Sudic D, Träskman-Bendz L, Landén M, Edman G, Vawter MP, Osby U, Schalling M. P2RX7: Expression responds to sleep deprivation and associates with rapid cycling in bipolar disorder type 1. PLoS One. 2012;7(8):e43057. Epub 2012 Aug 28.
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Torri F, Dinov ID, Zamanyan A, Hobel A, Genco A, Petrosyan P, Clark AP, Liu Z, Eggert P, Pierce J, Knowles JA, Ames J, Kesselman C, Toga AW, Potkin SG, Vawter MP, Macciardi F. Next generation sequence analysis and computational genomics using graphical pipeline workflows. Genes 2012; 3: 545-575.
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Sequeira A, Martin MV, Rollins B, Moon EA, Bunney WE, Macciardi F, Lupoli S, Smith EN, Kelsoe J, Magnan CN, van Oven M, Baldi P, Wallace DC and Vawter MP. Mitochondrial mutations and polymorphisms in psychiatric disorders. Front. Gene. 2012; 3:103.
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Sequeira A, Morgan L, Walsh DM, Cartagena PM, Choudary P, Li J, Schatzberg AF, Watson SJ, Akil H, Myers RM, Jones EG, Bunney WE, Vawter MP. Gene expression changes in the prefrontal cortex, anterior cingulate cortex and nucleus accumbens of mood disorders subjects that committed suicide. PLoS One. 2012;7(4):e35367. Epub 2012 Apr 30.
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2011
Vawter MP, Mamdani F, Macciardi F. An integrative functional genomics approach for discovering biomarkers in schizophrenia. Brief Funct Genomics. 2011 Nov;10(6):387-99. Epub 2011 Dec 8.
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Bellet MM, Vawter MP, Bunney BG, Bunney WE, Sassone-Corsi P. Ketamine influences CLOCK:BMAL1 function leading to altered circadian gene expression. PLoS One. 2011;6(8):e23982. Epub 2011 Aug 24.
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Moon E, Rollins B, Mesén A, Sequeira A, Myers RM, Akil H, Watson SJ, Barchas J, Jones EG, Schatzberg A, Bunney WE, DeLisi LE, Byerley W, Vawter MP. Lack of association to a NRG1 missense polymorphism in schizophrenia or bipolar disorder in a Costa Rican population. Schizophr Res. 2011 Sep;131(1-3):52-7. Epub 2011 Jul 13.
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Lee CS, Lee C, Hu T, Nguyen JM, Zhang J, Martin MV, Vawter MP, Huang EJ, Chan JY. Loss of nuclear factor E2-related factor 1 in the brain leads to dysregulation of proteasome gene expression and neurodegeneration. Proc Natl Acad Sci U S A. 2011 May 17;108(20):8408-13. Epub 2011 May 2.
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Sequeira PA, Martin MV, Vawter MP. The first decade and beyond of transcriptional profiling in schizophrenia. Neurobiol Dis. 2012 Jan;45(1):23-36. Epub 2011 Mar 8.
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2010
Potkin SG, Macciardi F, Guffanti G, Fallon JH, Wang Q, Turner JA, Lakatos A, Miles MF, Lander A, Vawter MP, Xie X. Identifying gene regulatory networks in schizophrenia. Neuroimage. 2010 Nov 15;53(3):839-47. Epub 2010 Jun 22.
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Rollins B, Martin MV, Morgan L, Vawter MP. 2010. Analysis of whole genome biomarker expression in blood and brain. Am J Med Genet B Neuropsychiatr Genet. 153B:919–936.
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Lavebratt, C., Sjoholm, L., Soronen, P., Paunio, T., Vawter, M., Bunney, W., Adolfsson, R., Forsell, Y., Wu, J., Kelsoe, J., Partonen, T., Shalling, M. (2010). CRY2 is Associated with Depression. PLos ONE 5(2).
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2009
Martin, M.V., Rollins, B. Sequeira, P.A., Mesen, A., Byerley, W., Stein, R., Moon, E.A., Akil, H., Jones, E.G., Watson, S.J., Barchas, J., Delisi, L.E., Myers, R.M., Schatzberg, A., Bunney, W.E., Vawter, M.P. (2009). Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation. BMC Med Genomics 2(1):62.
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Sequeira A, Mamdani F, Ernst C, Vawter MP, Bunney WE, Lebel V, Rehal S, Klempan T, Gratton A, Benkelfat C, Rouleau GA, Mechawar N, Turecki G. (2009). Global Brain Gene Expression Analysis Links Glutamatergic and GABAergic Alterations to Suicide and Major Depression. PLoS ONE 4(8):e6585.
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Rollins B, Martin MV, Sequeira PA, Moon EA, Morgan LZ, Watson SJ, Schatzberg A, Akil H, Myers RM, Jones EG, Wallace DC, Bunney WE, Vawter MP. (2009). Mitochondrial Variants in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder. PLoS ONE 4(3): e4913. doi:10.1371/journal.pone.0004913.
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Bertisch, H., Mesen-Fainardi, A., Martin, M.V., Pérez-Vargas, V., Vargas-Rodríguez, T., Delgado, G., Delgado, C., Llach, M., LaPrade, B., Byerley, W., Bunney, W.E., Vawter, M.P., DeLisi, L.E.; Pritzker Neuropsychiatric Research Consortium. (2009) Neuropsychological performance as endophenotypes in extended schizophrenia families from the Central Valley of Costa Rica. Psychiatr Genet. Feb;19(1):45-52.
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Altar, C.A., Vawter, M.P., Ginsberg, S.D. (2009) Target Identification for CNS Diseases by Transcriptional Profiling. Neuropsychopharmacology. Jan;34(1):18-54.
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2008
Shao, L., Martin, M.V., Watson, S.J., Schatzberg, A., Akil, H., Myers, R.M., Jones, E.G., Bunney, W.E., Vawter, M.P. (2008). Mitochondrial involvement in psychiatric disorders. Ann Med. 40(4):281-95. Review.
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Sequeira, A., Meng, F., Rollins, B., Myers, R.M., Jones, E.G., Watson, S.J., Akil, H., Schatzberg, A.F., Barchas, J., Bunney, W.E., Vawter, M.P. (2008). Coding SNPs included in exon arrays for the study of psychiatric disorders. Mol Psychiatry. 13(4):363-5.
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Shao, L., Vawter, M.P. (2008). Shared gene expression alterations in schizophrenia and bipolar disorder. Biol Psychiatry. 64(2):89-97.
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2007
Li, J.Z., Meng, F., Tsavaler, L., Evans, S.J., Choudary, P.V., Tomita, H., Vawter, M.P., Walsh, D., Shokoohi, V., Chung, T., Bunney, W.E., Jones, E.G., Akil, H., Watson, S.J., Myers, R.M. (2007). Sample matching by inferred agonal stress in gene expression analyses of the brain. 24(8):336.
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Atz, M.E., Walsh, D., Cartagena, P., Li, J., Evans, S., Choudary, P., Overman, K., Stein, R., Tomita, H., Potkin, S.G., Myers, R.M., Watson, S.J. Jones, E.G., Akil, H., Bunney, Jr., W.E., Vawter, M.P. (2007). Methodological considerations for gene expression profiling of human brain. J Neurosci Methods. 163(2):295-309.
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Vawter, M.P., Harvey, P.D., DeLisi, L.E. (2007). Dysregulation of X-linked gene expression in Klinefelter’s Syndrome and association with verbal cognition. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. Mar 8.
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Atz, M.E., Rollins, B., Vawter, M.P. (2007). Association of bipolar disorder with NCAM1 polymorphisms and alternatively spliced isoforms. Psychiatric Genetics. April, 17(2): 55-67.
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2006
Vawter, M.P., Atz, M.E., Rollins, B., Shao, L., Cooper-Casey, K.M., Byerley, W.F. (2006). Genome scans and gene expression microarrays: converging approaches to identify candidate genes and regulatory loci in schizophrenia. Human Genetics. 119(5):558-70.
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Vawter, M.P., Tomita, H., Meng, F., Bolstad, B., Li, J., Evans, S., Choudary, P., Atz, M.E., Shao, L., Neal, C., Walsh, D.M., Speed, T., Myers, R., Jones, E.G., Watson, S.J., Akil, H., Bunney, W.E. Jr. (2006). Mitochondrial related genes are sensitive to agonal-pH state: implications for brain disorders. Mol Psychiatry,11(7):615, 663-79.
PubMed | PDF | Tables 1-14 and Figures 1-3 | Gene List

Karssen, A.M., Li, J.Z., Her, S., Patel, P.D., Meng, F., Evans, S.J., Vawter, M.P., Tomita, H., Choudary, P.V., Bunney, W.E., Jones, E.G., Watson, S.J., Akil, H., Myers, R.M., Schatzberg, A.F., Lyons, D.M. (2006). Application of microarray technology in primate behavioral neuroscience research. Methods, 38, 227-234.
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2005
Choudary, P.V., Molnar, M., Evans, S.J., Tomita, H., Li, J.Z.,Vawter, M.P., Myers, R.M., Bunney, W.E., Akil, H., Watson, S.J., Jones, E.G. (2005). Altered cortical glutamate and GABA signaling and glial cell involvement in major depression. Proceedings National Academy Science, 102(43), 15653-8.
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2004
Vawter, M.P. , Ferran, E., Galke, B., Cooper, K.C., Bunney, W.E., Byerley, W. (2004). Microarray screening of lymphocyte gene expression differences in a multiplex schizophrenia pedigree. Schizophrenia Research 67(1):41-52.
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Evans, S.J., Choudary, P.V., Neal, C.R., Li, J.Z., Vawter, M.P., Tomita, H., Lopez, J.F., Thompson, R.C., Meng, F., Stead, J.D., Walsh, D.M., Myers, R.M., Bunney, W.E., Watson, S.J., Jones, E.G., Akil, H. (2004). Dysregulation of the fibroblast growth factor system in major depression. Proceedings National Academy Science, 101(43):15506-11.
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Li, J.Z., Vawter, M.P., Walsh, D.M., Tomita, H., Evans, S.J., Choudary, P.V., Lopez, J.F., Avelar,A., Shokoohi, V., Chung, T., Mesarwi, O., Jones, E.G., Watson, S.J., Akil, H., Bunney, W.E., Myers, R.M. (2004). Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions. Human Molecular Genetics, 13(6):609-16.
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Tomita*,H., Vawter*, M.P., Walsh*, D.M., Evans, S.J., Choudary, P.V., Li, J., Overman, K.M., Atz, M. E. , Myers, R.M., Jones E. G., Watson, S.J., Akil, H., Bunney, W.E. Jr. (2004). Postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain. Biological Psychiatry 55(4), 346-352. *Authors contributed equally to the work.
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*Vawter, M.P., *Evans, S.J., *Choudary, P.V., *Tomita, H., Meador-Woodruff, J.H., Molnar, M., Lopez J.F., Li J., Myers R.M., Akil H., Watson S.J., Jones E.G., Bunney W.E. (2004). Gender specific gene expression in postmortem human brain: localization to sex chromosomes. Neuropsychopharmacology,29(2):373-84.*Authors contributed equally to the work.
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Vawter, M.P., Shannon Weickert, C., Ferran, E., Matsumoto, M.,Overman, K., Hyde, T.M., Weinberger, D.R., Bunney, W.E., Kleinman, J.E. (2004). Gene expression of metabolic enzymes and a protease inhibitor in the prefrontal cortex are decreased in schizophrenia. Neurochem Res. 29 (6): 1245-1255.
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2003
*Evans, S.J., *Choudary, P.V., *Vawter M.P., Li J., Meador-Woodruff, J.H., Lopez, J.F., Burke, S.M., Thompson, R.C., Myers, R.M., Jones, E.G., Bunney, W.E., Watson, S.J., and Akil, H. (2003). DNA microarray analysis of functionally discrete human brain regions reveals divergent transcriptional profiles. Neurobiology of Disease 14, 240-250. *Authors contributed equally to the work.
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Bunney, W.E., Bunney, B.G., Vawter, M.P., Tomita, H., Li, J., Evans, S.J., Choudray, P., Myers, R.M., Jones, E.G., Watson, S.J., Akil, H. (2003). Microarray technology: a review of new strategies to discover candidate vulnerability genes in psychiatric disorders. American Journal of Psychiatry, 160 (4), 657-666.
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Comi, A.M., Hunt, P., Vawter, M.P., Pardo, C.A., Becker, K.G., Pevsner, J. (2003). Increased fibronectin expression in sturge-weber syndrome fibroblasts and brain tissue. Pediatr Res. 53(5):762-9.
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Lehrmann, E., Oyler, J., Vawter, M.P., Hyde, T.M., Kolachana, B., Kleinman, J.E., Huestis, M.A., Becker, K.G., Freed, W.J. (2003). Transcriptional profiling in the human prefrontal cortex: evidence for two activational states associated with cocaine abuse. Pharmacogenomics J. 3(1):27-40.
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Thompson, P.M., Egbufoama, S., Vawter, M.P. (2003). SNAP-25 reduction in the hippocampus of patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 27(3):411-7.
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Cheadle, C., Vawter, M.P., Freed, W.J., Becker, K.G. (2003). Analysis of microarray data using Z score transformation. J Mol Diagn. 5(2):73-81.
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Lehrmann, E., Hyde, T.M., Vawter, M.P., Becker, K.G., Kleinman, J.E., Freed, W.J. (2003). The use of microarrays to characterize neuropsychiatric disorders: postmortem studies of substance abuse and schizophrenia. Curr Mol Med. 3(5):437-46.
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Blaabjerg, M., Baskys, A., Zimmer, J., Vawter, M.P. (2003). Changes in hippocampal gene expression after neuroprotective activation of group I metabotropic glutamate receptors. Brain Res Mol Brain Res. 117(2):196-205.
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2002
Truckenmiller, M.E., Vawter, M.P., Zhang P., Conejero-Goldberg, C., Dillon-Carter, O., Morales, N., Cheadle, C., Becker, K.G., Freed, W.J. (2002). AF5, a CNS cell line immortalized with an N-terminal fragment of SV40 large T: growth, differentiation, genetic stability, and gene expression. Exp Neurol. Jun;175(2):318-37.
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Vawter, M.P., Thatcher, L., Usen, N., Hyde, T.M., Kleinman, J.E., Freed, W.J. (2002). Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia. Mol Psychiatry. 7(6):571-8.
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Vawter, M.P., Crook, J.M., Hyde, T.M., Kleinman, J.E., Weinberger, D.R., Becker, K.G., Freed, W.J. (2002). Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study.Schizophr Res. 58(1):11-20.
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2001
Konu, O., Kane, J.K., Barrett, T., Vawter, M.P., Chang, R., Ma, J.Z., Donovan, D.M., Sharp, B., Becker, K.G., Li, M.D. (2001). Region-specific transcriptional response to chronic nicotine in rat brain. Brain Res. 909(1-2):194-203.
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Vawter, M.P., Barrett, T., Cheadle, C., Sokolov, B.P., Wood, W.H. 3rd, Donovan, D.M., Webster,M., Freed, W.J., Becker, K.G. (2001). Application of cDNA microarrays to examine gene expression differences in schizophrenia. Brain Res Bull. Jul 15;55(5):641-50.
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Barrett, T., Xie, T., Piao, Y., Dillon-Carter, O., Kargul, G.J., Lim, M.K., Chrest, F.J., Wersto, R., Rowley, D.L., Juhaszova, M., Zhou, L., Vawter, M.P., Becker, K.G., Cheadle, C., Wood, W.H. 3rd, McCann, U.D., Freed, W.J., Ko, M.S., Ricaurte, G.A., Donovan, D.M. (2001). A murine dopamine neuron-specific cDNA library and microarray: increased COX1 expression during methamphetamine neurotoxicity. Neurobiol Dis. 8(5):822-33.
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Vawter, M.P., Usen, N., Thatcher, L., Ladenheim, B., Zhang, P., VanderPutten, D.M., Conant, K., Herman, M.M., van Kammen, D.P., Sedvall, G., Garver, D.L., Freed, W.J. (2001). Characterization of human cleaved N-CAM and association with schizophrenia. Exp Neurol. 172(1):29-46.
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Freed, W.J., Vawter, M.P. (2001). Microarrays: applications in neuroscience to disease, development, and repair. Restor Neurol Neurosci. 18(2-3):53-6.
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Truckenmiller, M.E., Vawter, M.P., Cheadle, C., Coggiano, M., Donovan, D.M., Freed, W.J., Becker, K.G. (2001). Gene expression profile in early stage of retinoic acid-induced differentiation of human SH-SY5Y neuroblastoma cells. Restor Neurol Neurosci. 18(2-3):67-80.
PubMed

Barrett, T., Cheadle, C., Wood, W.B., Teichberg, D., Donovan, D.M., Freed, W.J., Becker, K.G., Vawter, M.P. (2001). Assembly and use of a broadly applicable neural cDNA microarray. Restor Neurol Neurosci. 18(2-3):127-35.
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Collaborations

Goes FS, Rongione M, Chen YC, Karchin R, Elhaik E; Bipolar Genome Study, Potash JB. Exonic DNA sequencing of ERBB4 in bipolar disorder. Collaborators (110)Kelsoe JR, Greenwood TA, Nievergelt CM, McKinney R, Shilling PD, Schork N, Smith EN, Bloss C, Nurnberger J, Edenberg HJ, Foroud T, Koller DL, Gershon E, Liu C, Badner JA, Scheftner WA, Lawson WB, Nwulia EA, Hipolito M, Coryell W, Rice J, Byerley W, McMahon F, Schulze TG, Berrettini W, Potash JB, Zandi PP, Mahon PB, McInnis MG, Zöllner S, Zhang P, Craig DW, Szelinger S, Barrett TB, Nurnberger J, Miller M, Bowman E, Reich T, Goate A, Rice J, DePaulo JR Jr, Simpson S, Stine C, Gershon E, Kazuba D, Maxwell E, Nurnberger J, Miller MJ, Bowman ES, Rau NL, Moe PR, Samavedy N, El-Mallakh R, Manji H, Glitz A, Meyer ET, Smiley C, Foroud T, Flury L, Dick DM, Edenberg H, Rice J, Reich T, Goate A, Bierut L, McInnis M, DePaulo JR Jr, MacKinnon DF, Mondimore FM, Potash JB, Zandi PP, Avramopoulos D, Payne J, Berrettini W, Byerley W, Vawter M, Coryell W, Crowe R, Gershon E, Badner J, McMahon F, Liu C, Sanders A, Caserta M, Dinwiddie S, Nguyen T, Harakal D, Kelsoe JR, McKinney R, Scheftner W, Kravitz HM, Marta D, Vaughn-Brown A, Bederow L, Kassem L, Detera-Wadleigh S, Austin L, Murphy DL, Gejman PV, Sanders AR, Amin F, Buccola N, Byerley W, Cloninger CR, Crowe R, Black D, Freedman R, Levinson D, Mowry B, Silverman J. PLoS One.2011;6(5):e20242. Epub 2011 May 26.
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Belmonte Mahon P, Pirooznia M, Goes FS, Seifuddin F, Steele J, Lee PH, Huang J, Hamshere ML; Bipolar Genome Study (BiGS) Consortium, The Wellcome Trust Case Control Consortium Bipolar Disorder Group, Depaulo JR Jr, Kelsoe JR, Rietschel M, Nöthen M, Cichon S, Gurling H, Purcell S, Smoller JW, Craddock N, Schulze TG, McMahon FJ, Potash JB, Zandi PP. Collaborators (186)Nurnberger J, Miller M, Bowman E, Reich T, Goate A, Rice J, DePaulo JR Jr, Simpson S, Stine C, Gershon E, Kazuba D, Maxwell E, Nurnberger J, Miller MJ, Bowman ES, Rau L, Moe PR, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Foroud T, Flury L, Dick DM, Edenberg H, Rice J, Reich T, Goate A, Bierut L, McInnis M, DePaulo JR Jr, MacKinnon DF, Mondimore FM, Potash JB, Zandi PP, Avramopoulos D, Payne J, Berrettini W, Byerley W, Vawter M, Coryell W, Crowe R, Gershon E, Badner J, McMahon F, Liu C, Sanders A, Caserta M, Dinwiddie S, Nguyen T, Harakal D, Kelsoe J, McKinney R, Scheftnerv W, Kravitz HM, Marta D, Vaughn-Brown A, Bederow L, McMahon FJ, Kassem L, Detera-Wadleigh S, Austin L, Murphy DL, Nurnberger J, Miller MJ, Bowman ES, Rau NL, Moe PR, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Foroud T, Flury L, Dick DM, Edenberg H, Rice J, Reich T, Goate A, Bierut L, McInnis M, DePaulo JR Jr, MacKinnon DF, Mondimore FM, Potash JB, Zandi PP, Avramopoulos D, Payne J, Berrettini W, Byerley W, Vinogradov S, Coryell W, Crowe R, Gershon E, Badner J, McMahon F, Liu C, Sanders A, Caserta M, Dinwiddie S, Nguyen T, Harakal D, Kelsoe J, McKinney R, Scheftner W, Kravitz HM, Marta D, Vaughn-Brown A, Bederow L, McMahon FJ, Kassem L, Detera-Wadleigh S, Austin L, Murphy DL, Lawson WB, Nwulia E, Hipolito M, Gejman PV, Sanders AR, Amin F, Buccola N, Byerley W, Cloninger CR, Crowe R, Black D, Freedman R, Levinson D, Mowry B, Silverman J, Kelsoe JR, Greenwood TA, Shilling PD, Nievergelt C, Schork N, Smith EN, Nurnberger J, Edenberg HJ, Foroud T, Gershon E, Liu C, Badner JA, Scheftner WA, Lawson WB, Nwulia EA, Hipolito M, Coryell W, Rice J, Byerley W, McMahon F, Schulze TG, Berrettini W, Potash JB, Zandi PP, Mahon PB, McInnis MG, Zöllner S, Craig D, Szelinger S, Breen G, Clair DS, Caesar S, Gordon-Smith K, Jones L, Fraser C, Green EK, Grozeva D, Hamshere ML, Holmans PA, Jones IR, Kirov G, Moskvina V, Nikolov I, O’Donovan MC, Owen MJ, Craddock N, Collier DA, Elkin A, Farmer A, Williamson R, McGuffin P, Young AH, Ferrier IN.Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2011 Apr;156B(3):370-8. doi: 10.1002/ajmg.b.31172. Epub 2011 Feb 8. Erratum in: Am J Med Genet B Neuropsychiatr Genet. 2011 Sep;156B(6):749-50.
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Willour VL, Chen H, Toolan J, Belmonte P, Cutler DJ, Goes FS, Zandi PP, Lee RS, MacKinnon DF, Mondimore FM, Schweizer B; Bipolar Disorder Phenome Group; NIMH Genetics Initiative Bipolar Disorder Consortium, DePaulo JR Jr, Gershon ES, McMahon FJ, Potash JB. Collaborators: McMahon F, Steele J, Pearl J, Kassem L, Lopez V, Potash J, MacKinnon D, Miller E, Toolan J, Zandi P, Schulze T, Nwulia E, Simpson S, Nurnberger J, Miller M, Bowman E, Reich T, Goate A, Rice J, DePaulo JR Jr, Simpson S, Stine C, Gershon E, Kazuba D, Maxwell E, Nurnberger J, Miller MJ, Bowman ES, Rau NL, Moe PR, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Foroud T, Flury L, Dick DM, Edenberg H, Rice J, Reich T, Goate A, Bierut L, McInnis M, DePaulo JR Jr, MacKinnon DF, Mondimore FM, Potash JB, Zandi PP, Avramopoulos D, Payne J, Berrettini W, Byerley W, Vawter M, Coryell W, Crowe R, Gershon E, Badner J, McMahon F, Liu C, Sanders A, Caserta M, Dinwiddie S, Nguyen T, Harakal D, Kelsoe J, McKinney R, Scheftner W, Kravitz HM, Marta D, Vaughn-Brown A, Bederow L, McMahon FJ, Kassem L, Detera-Wadleigh S, Austin L, Murphy DL. (2009). Family-based association of FKBP5 in bipolar disorder. Mol Psychiatry. 14(3):261-8.
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Payne JL, Klein SR, Zamoiski RB, Zandi PP, Bienvenu OJ, Mackinnon DF, Mondimore FM, Schweizer B, Swartz KL; NIMH Genetics Initiative Bipolar Disorder Consortium, Crowe RP, Scheftner WA, Weissman MM, Levinson DF, DePaulo JR Jr, Potash JB. Collaborators: Nurnberger J, Miller MJ, Bowman ES, Rau NL, Moe PR Jr, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Foroud T, Flury L, Dick DM, Edenberg H, Rice J, Reich T, Goate A, Bierut L, McInnis M, DePaulo JR Jr

MacKinnon DF, Mondimore FM, Potash JB, Zandi PP, Avramopoulos D, Payne J, Berrettini W, Byerley W, Vawter M, Coryell W, Crowe R, Gershon E, Badner J, McMahon F, Liu C, Sanders A, Caserta M, Dinwiddie S, Nguyen T, Harakal D, Kelsoe J, McKinney R, Scheftner W, Kravitz HM, Marta D, Vaughn-Brown A, Bederow L, McMahon FJ, Kassem L, Detera-Wadleigh S, Austin L, Murphy DL. (2009). Premenstrual mood symptoms: study of familiality and personality correlates in mood disorder pedigrees. Arch Womens Ment Health. 12(1):27-34.
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Zandi, P.P., Belmonte, P.L., Willour, V.L., Goes, F.S., Badner, J.A., Simpson, S.G., Gershon, E.S., McMahon, F.J., DePaulo, J.R. Jr, Potash, J.B.; Bipolar Disorder Phenome Group; National Institute of Mental Health Genetics Initiative Bipolar Disorder Consortium. Collaborators:

Nurnberger, Miller MJ, Bowman ES, Reich T, Goate , Rice , DePaulo , Simpson , Stine C, Gershon , Kazuba D, Maxwell E, Miller , Bowman , Rau NL, Moe PR, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Foroud T, Flury L, Dick DM, Edenberg H, Rice , Reich , Goate , Bierut L, McInnis M, DePaulo , MacKinnon DF, Mondimore FM, Potash , Zandi , Avramopoulos D, Payne J, Berrettini W, Byerley

Vawter M, Coryell , Crowe R, Gershon , Badner , McMahon , Liu C, Sanders A, Caserta M, Dinwiddie S, Nguyen T, Harakal D, Kelsoe , McKinney R, Scheftner W, Kravitz HM, Marta D, Vaughn-Brown A, Bederow L, McMahon , Kassem L, Detera-Wadleigh S, Austin S, Murphy DL. (2008). Association study of Wnt signaling pathway genes in bipolar disorder. Arch Gen Psychiatry. 65(7):785-93.
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Sklar P, Smoller JW, Fan J, Ferreira MA, Perlis RH, Chambert K, Nimgaonkar VL, McQueen MB, Faraone SV, Kirby A, de Bakker PI, Ogdie MN, Thase ME, Sachs GS, Todd-Brown K, Gabriel SB, Sougnez C, Gates C, Blumenstiel B, Defelice M, Ardlie KG, Franklin J, Muir WJ, McGhee KA, MacIntyre DJ, McLean A, VanBeck M, McQuillin A, Bass NJ, Robinson M, Lawrence J, Anjorin A, Curtis D, Scolnick EM, Daly MJ, Blackwood DH, Gurling HM, Purcell SM.

Collaborators: Marangell LB, Calabrese JR, Nierenberg AA, Hauser P, Ketter TA, Thomas M, Patel J, Fossey MD, Gyulai L, Thase ME, Bowden CL, Molay F, Rosen-Sheidley B, Silfies L, Gejman PV, Sanders AR, Amin F, Buccola N, Byerley W, Cloninger CR, Crowe R, Black D, Freedman R, Levinson D, Mowry B, Silverman J, Nurnberger J, Miller MJ, Bowman ES, Rau NL, Moe PR, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Foroud T, Flury L, Dick DM, Edenberg H, Rice J, Reich T, Goate A, Bierut L, McInnis M, DePaulo JR Jr, MacKinnon DF, Mondimore FM, Potash JB, Zandi PP, Avramopoulos D, Payne J, Berrettini W, Byerley W, Vawter M, Coryell W, Crowe R, Gershon E, Badner J, McMahon F, Liu C, Sanders A, Caserta M, Dinwiddie S, Nguyen T, Harakal D, Kelsoe J, McKinney R, Scheftner W, Kravitz HM, Marta D, Vaughn-Brown A, Bederow L, McMahon FJ, Kassem L, Detera-Wadleigh S, Austin L, Murphy DL. (2008).

Whole-genome association study of bipolar disorder. Mol Psychiatry Jun;13(6):558-69.
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