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Progesterone suppresses the progression of colonic carcinoma by increasing the activity of the GADD45α/JNK/c‑Jun signalling pathway

Progesterone suppresses the progression of colonic carcinoma by increasing the activity of the GADD45α/JNK/c‑Jun signalling pathway

Posted on May 13, 2021April 23, 2021 by Vawter

Colorectal most cancers (CRC) is the third most identified most cancers worldwide. Progesterone is related to a decreased danger of CRC and results in a beneficial prognosis. Nonetheless, the precise mechanism by which progesterone suppresses malignant development stays to be elucidated. Within the current research, the extent of progesterone was first analysed in 77 sufferers with CRC, and immunohistochemistry was carried out to detect the expression of progesterone receptor (PGR) within the paired specimens. The correlations between progesterone, PGR and CRC prognosis had been assessed. A Cell Counting Package‑eight assay was then used to detect proliferation of the CRC cells. Circulation cytometry was carried out to estimate apoptosis and to guage the cycle of the CRC cells.

A xenograft tumour mannequin was established in nude mice to evaluate the function of progesterone in tumour development. Lastly, a PCR microarray was used to display screen differentially expressed genes to additional interpret the mechanism by which progesterone inhibits the malignant development of CRC. It was discovered that low expression of progesterone and PGR had been considerably related to poor prognosis of CRC. As well as, progesterone suppressed CRC cell proliferation by arresting the cell cycle and inducing apoptosis in vitro. Furthermore, the inhibitory function of progesterone in tumour development was verified in vivo.

Additional investigation confirmed that the extent of development arrest and DNA harm‑inducible protein α (GADD45α) was up‑regulated by progesterone, and this was adopted by the activation of the JNK pathway. Progesterone elevated the exercise of the JNK pathway through GADD45α to inhibit proliferation by arresting the cell cycle and inducing apoptosis, thereby suppressing the malignant development of CRC. Subsequently, it may be concluded that progesterone and PGR may act as inhibiting elements for poor prognosis of CRC.

Decide the incremental yield of subsequent technology sequencing (predominantly exome sequencing (ES)) over quantitative fluorescence-polymerase chain response (QF-PCR) and chromosome microarray evaluation (CMA)/karyotyping in; (i) all instances of prenatally identified non-immune hydrops fetalis (NIHF); (ii) remoted NIHF; (iii) NIHF related to further structural anomalies and; (iv) NIHF in line with severity (i.e., two cavities versus three or extra cavities affected).

MiRNA expression profiling and emergence of latest prognostic signature for oral squamous cell carcinoma

Oral squamous cell carcinoma (OSCC), the commonest sort of head and neck cancers, is related to excessive recurrence, metastasis, low long-term survival charges and poor remedy consequence. As deregulated miRNA expression performs an important function in malignant transformation and most cancers development, the current research is aimed toward profiling the miRNA expression sample in OSCC and creating a brand new miRNA prognostic signature for oral most cancers. MiRNA expression profiling was carried out utilizing MiRNA microarray in 30 tumor and 18 regular samples. MiRNA signature obtained was validated with quantitative actual time PCR (qRT-PCR) in 144 tumor and 36 regular samples.

The potential targets, scientific implications and prognostic worth of the miRNA signature had been elucidated by numerous bioinformatics and statistical analyses. Microarray profiling recognized a set of 105 miRNAs to be differentially expressed in OSCC, out of which a subset of 19 most dysregulated miRNAs had been validated by qRT-PCR. In silico evaluation revealed the signature miRNAs to be concerned in numerous most cancers related pathways. Up-regulation of miR-196a, miR-21, miR-1237 and downregulation of miR-204, miR-144 was related to poor prognosis of OSCC sufferers. The mir-196a/miR-204 expression ratio emerged as finest predictor for illness recurrence and affected person survival. Altogether, our research recognized a miRNA signature for OSCC with prognostic significance.

Progesterone suppresses the progression of colonic carcinoma by increasing the activity of the GADD45α/JNK/c‑Jun signalling pathway

Identification of fibroblast activation-related genes in two acute kidney harm fashions

Ischemia-reperfusion harm and drug-induced nephrotoxicity are the 2 most typical causes for acute kidney harm (AKI). Nonetheless, little consideration has been paid to early activation of fibroblasts within the development of AKI to persistent kidney illness (CKD). The current research aimed to determine associated genes and pathways on fibroblast activation in two mouse fashions of AKI: ischemia-reperfusion harm (IRI) mannequin and folic acid (FA)-induced harm mannequin. The microarray expression profiles of GSE62732 and GSE121190 had been downloaded from the GEO database, and the differentially expressed genes (DEGs) was analyzed utilizing the Limma bundle of R software program.

Principal element evaluation (PCA) was additionally carried out utilizing R. The practical info of gene merchandise was annotated by Gene Ontology (GO) and DAVID on-line database, and the pathway evaluation was carried out through the use of the Kyoto Encyclopedia of Genes and Genomes pathway (KEGG) database. Protein-protein interactions (PPI) community was constructed by STRING and Cytoscape. Moreover, within the Hypoxia/Reoxygenation (H/R) mannequin, the morphological adjustments of cells had been noticed beneath microscope and the expression of the hub genes in NRK-49F cells had been validated by qRT-PCR assays. A complete of 457 DEGs had been recognized.

Alpha-bungarotoxin, CF640r

9-00004 Biotium
  • EUR 592.80
  • EUR 193.20
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 100uG

Alpha-bungarotoxin, CF488a

9-00005 Biotium
  • EUR 592.80
  • EUR 193.20
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 500uG

Alpha-bungarotoxin CF488a

9-00005 Biotium
  • EUR 592.80
  • EUR 193.20
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 100uG

Alpha-bungarotoxin, CF568

9-00006 Biotium
  • EUR 592.80
  • EUR 193.20
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 500uG

Alpha-bungarotoxin, CF568

9-00006 Biotium
  • EUR 592.80
  • EUR 193.20
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 100uG

Alpha-bungarotoxin, CF594

9-00007 Biotium
  • EUR 592.80
  • EUR 193.20
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 500uG

Alpha-bungarotoxin CF594

9-00007 Biotium
  • EUR 592.80
  • EUR 193.20
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 100uG

Alpha-bungarotoxin, CF633

9-00009 Biotium
  • EUR 592.80
  • EUR 193.20
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 500uG

Alpha-bungarotoxin, CF633

9-00009 Biotium
  • EUR 592.80
  • EUR 193.20
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 100uG

Alpha-bungarotoxin

00010-1 Biotium 1MG
EUR 201.6
Description: Minimum order quantity: 1 unit of 1MG

Fluorescein-Alpha-bungarotoxin

00011 Biotium 500uG
EUR 440.4
Description: Minimum order quantity: 1 unit of 500uG

Tetramethylrhodamine-Alpha-bungarotoxin

00012 Biotium 500uG
EUR 459.6
Description: Minimum order quantity: 1 unit of 500uG

Fluorescein-alpha-bungarotoxin: (10x50ug)

00013 Biotium 10ST
EUR 500.4
Description: Minimum order quantity: 1 unit of 10ST

Tetramethylrhodamine-alpha-bungarotoxin: (10x50ug)

00014 Biotium 10ST
EUR 559.2
Description: Minimum order quantity: 1 unit of 10ST

Sulforhodamine 101-a-bungarotoxin (Texas Red--a-bungarotoxin): (500ug)

00015 Biotium 500uG
EUR 559.2
Description: Minimum order quantity: 1 unit of 500uG

Sulforhodamine 101-a-bungarotoxin (Texas Red--a-bungarotoxin): (10x50ug)

00016 Biotium 10ST
EUR 627.6
Description: Minimum order quantity: 1 unit of 10ST

Biotin-xx-a-bungarotoxin

00017 Biotium 500uG
EUR 519.6
Description: Minimum order quantity: 1 unit of 500uG

Alpha-Bungarotoxin, CF555 conjugate

9-00018 Biotium
  • EUR 592.80
  • EUR 193.20
  • 500uG
  • 100ug
Description: Minimum order quantity: 1 unit of 500uG

Alpha-Bungarotoxin, CF555 conjugate

9-00018 Biotium
  • EUR 592.80
  • EUR 193.20
  • 500uG
  • 100ug
Description: Minimum order quantity: 1 unit of 100ug

Biotin-cAMP, diisopropylethylammonium salt:

00020 Biotium 1MG
EUR 376.8
Description: Minimum order quantity: 1 unit of 1MG

Biotin-cAMP, diisopropylethylammonium salt: (20x50ug)

00020-1 Biotium 20ST
EUR 501.6
Description: Minimum order quantity: 1 unit of 20ST

Biotin-cGMP, diisopropylethylammonium salt:

00021 Biotium 1MG
EUR 412.8
Description: Minimum order quantity: 1 unit of 1MG

Biotin-cGMP, diisopropylethylammonium salt: (20x50ug)

00021-1 Biotium 20ST
EUR 537.6
Description: Minimum order quantity: 1 unit of 20ST

Cyanine 644-cAMP:

00022 Biotium 1MG
EUR 589.2
Description: Minimum order quantity: 1 unit of 1MG

Cyanine 644-cAMP: (20x50ug)

00022-1 Biotium 20ST
EUR 750
Description: Minimum order quantity: 1 unit of 20ST

Fluorescein Methotrexate, triammonium salt:

00023 Biotium 1MG
EUR 337.2
Description: Minimum order quantity: 1 unit of 1MG

Staurosporine

00025 Biotium 100uG
EUR 166.8
Description: Minimum order quantity: 1 unit of 100uG

Alpha-bungarotoxin, CF543

00026 Biotium 500uG
EUR 592.8
Description: Minimum order quantity: 1 unit of 500uG

Rhodamine phalloidin 300u

00027 Biotium 300
EUR 414
Description: Minimum order quantity: 1 unit of 300

Biotin-xx-phalloidin

00028 Biotium 100U
EUR 513.6
Description: Minimum order quantity: 1 unit of 100U

Fluorescein-phalloidin

00030 Biotium 300U
EUR 414
Description: Minimum order quantity: 1 unit of 300U

Rhodamine 110 phalloidin

00032 Biotium 300ST
EUR 414
Description: Minimum order quantity: 1 unit of 300ST

Sulforhodamine 101 (Texas-Red) Phalloidin

00033 Biotium 300EU
EUR 414
Description: Minimum order quantity: 1 unit of 300EU

Phalloidin, CF405M

00034 Biotium 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF405M

00034-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

CF488A-cAMP

00036 Biotium 100ug
EUR 206.4
Description: Minimum order quantity: 1 unit of 100ug

CF640R-cAMP

00037 Biotium 100ug
EUR 206.4
Description: Minimum order quantity: 1 unit of 100ug

Phalloidin, CF555

00040 Biotium 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF555

00040-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF647

00041 Biotium 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF647

00041-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF488A

00042 Biotium 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF488A

00042-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF543

00043 Biotium 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF543

00043-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF568

00044 Biotium 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF568

00044-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF594

00045 Biotium 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF594

00045-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF633

00046 Biotium 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF633

00046-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF660R

00047 Biotium 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF660R

00047-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF680R

00048 Biotium 300U
EUR 559.2
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF680R

00048-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF350

00049 Biotium 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF350

00049-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF640R

00050 Biotium 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF640R

00050-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF532

00051 Biotium 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF532

00051-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF660C

00052 Biotium 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF660C

00052-T Biotium 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF680

00053 Biotium 300U
EUR 559.2
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF680

00053-T Biotium 50U
EUR 176.4
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF430

00054 Biotium 300U
EUR 538.8
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF430

00054-T Biotium 50U
EUR 166.8
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF440

00055 Biotium 300U
EUR 538.8
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF440

00055-T Biotium 50U
EUR 166.8
Description: Minimum order quantity: 1 unit of 50U

Cholera Toxin Subunit B, CF488A conjugate

00070 Biotium 100ug
EUR 313.2
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF568 conjugate

00071 Biotium 100ug
EUR 313.2
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF594 conjugate

00072 Biotium 100ug
EUR 313.2
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF640R conjugate

00073 Biotium 100ug
EUR 316.8
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF532 conjugate

00074 Biotium 100ug
EUR 316.8
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF543 conjugate

00075 Biotium 100ug
EUR 316.8
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF620R conjugate

00076 Biotium 100ug
EUR 316.8
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF633 conjugate

00077 Biotium 100ug
EUR 316.8
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF660R conjugate

00078 Biotium 100ug
EUR 316.8
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF680R conjugate

00079 Biotium 100ug
EUR 338.4
Description: Minimum order quantity: 1 unit of 100ug

Human Transferrin, CF488A conjugate

00081 Biotium 1mg
EUR 178.8
Description: Minimum order quantity: 1 unit of 1mg

Human Transferrin, CF543 conjugate

00082 Biotium 1mg
EUR 178.8
Description: Minimum order quantity: 1 unit of 1mg

Human Transferrin, CF568 conjugate

00083 Biotium 1mg
EUR 178.8
Description: Minimum order quantity: 1 unit of 1mg

Human Transferrin, CF594 conjugate

00084 Biotium 1mg
EUR 178.8
Description: Minimum order quantity: 1 unit of 1mg

Human Transferrin, CF640R conjugate

00085 Biotium 1mg
EUR 178.8
Description: Minimum order quantity: 1 unit of 1mg

Human Transferrin, CF680R conjugate

00086 Biotium 1mg
EUR 178.8
Description: Minimum order quantity: 1 unit of 1mg

Human Transferrin, CF750 conjugate

00087 Biotium 1mg
EUR 186
Description: Minimum order quantity: 1 unit of 1mg

HIV-1 tat recombinant antigen

00110-V-01mg Virogen 0,1 mg
EUR 321
Description: HIV-1 tat recombinant antigen full length 15 kDa

HIV-1 tat recombinant antigen

00110-V-1000ug Virogen 1000 ug
EUR 1539
Description: HIV-1 tat recombinant antigen full length 15 kDa

HIV-1 GAG P24 Recombinant Antigen

00111-V-01mg Virogen 0,1 mg
EUR 321
Description: HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa

HIV-1 GAG P24 Recombinant Antigen

00111-V-1000ug Virogen 1000 ug
EUR 1539
Description: HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa

HIV-1 nef recombinant antigen

00112-V-01mg Virogen 0,1 mg
EUR 321
Description: HIV-1 nef recombinant antigen a.a 3 to a.a 190 of the HIV-1 nef region 20 kDa

HIV-1 nef recombinant antigen

00112-V-1000ug Virogen 1000 ug
EUR 1539
Description: HIV-1 nef recombinant antigen a.a 3 to a.a 190 of the HIV-1 nef region 20 kDa

HIV-1 env gp41 recombinant antigen

00113-V-01mg Virogen 0,1 mg
EUR 321
Description: HIV-1 env gp41 recombinant antigen a.a 466 to a.a 753 of the HIV-1 env region 32 kDa

HIV-1 env gp41 recombinant antigen

00113-V-1000ug Virogen 1000 ug
EUR 1539
Description: HIV-1 env gp41 recombinant antigen a.a 466 to a.a 753 of the HIV-1 env region 32 kDa

HIV-2 GP 36 Recombinant Antigen

00114-V-01mg Virogen 0,1 mg
EUR 321
Description: HIV -2 env gp36 recombinant antigen a.a 390 to a.a 702 of the HIV-2 env region 34 kDa

HIV-2 GP 36 Recombinant Antigen

00114-V-1000ug Virogen 1000 ug
EUR 1539
Description: HIV -2 env gp36 recombinant antigen a.a 390 to a.a 702 of the HIV-2 env region 34 kDa

HCV core recombinant antigen

00115-V-01mg Virogen 0,1 mg
EUR 321
Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa

HCV core recombinant antigen

00115-V-1000ug Virogen 1000 ug
EUR 1539
Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa

HCV core recombinant antigen, Biotin conjugate

00115-V-B-01mg Virogen 0,1 mg
EUR 321
Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa. Biotin conjugate.

HCV core recombinant antigen, Biotin conjugate

00115-V-B-1000ug Virogen 1000 ug
EUR 1539
Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa. Biotin conjugate.

HCV core recombinant antigen, FITC conjugate

00115-V-F-01mg Virogen 0,1 mg
EUR 321
Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa. Fluorescein conjugate.

HCV core recombinant antigen, FITC conjugate

00115-V-F-1000ug Virogen 1000 ug
EUR 1539
Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa. Fluorescein conjugate.

HCV core recombinant antigen, Rhodamine

00115-V-R-01mg Virogen 0,1 mg
EUR 321
Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa . Rhodamine conjugate.

HCV core recombinant antigen, Rhodamine

00115-V-R-1000ug Virogen 1000 ug
EUR 1539
Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa . Rhodamine conjugate.

HCV NS4 recombinant antigen NS4a+b

00116-V-01mg Virogen 0,1 mg
EUR 321
Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa.

HCV NS4 recombinant antigen NS4a+b

00116-V-1000ug Virogen 1000 ug
EUR 1539
Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa.

HCV NS4 recombinant antigen NS4a+b, Biotin

00116-V-B-01mg Virogen 0,1 mg
EUR 321
Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Biotin conjugate.

HCV NS4 recombinant antigen NS4a+b, Biotin

00116-V-B-1000ug Virogen 1000 ug
EUR 1539
Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Biotin conjugate.

HCV NS4 recombinant antigen NS4a+b, FITC

00116-V-F-01mg Virogen 0,1 mg
EUR 321
Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Fluorescein conjugate.

HCV NS4 recombinant antigen NS4a+b, FITC

00116-V-F-1000ug Virogen 1000 ug
EUR 1539
Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Fluorescein conjugate.

HCV NS4 recombinant antigen NS4a+b, Rhodamine

00116-V-R-01mg Virogen 0,1 mg
EUR 321
Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Rhodamine conjugate.

HCV NS4 recombinant antigen NS4a+b, Rhodamine

00116-V-R-1000ug Virogen 1000 ug
EUR 1539
Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Rhodamine conjugate.

HCV NS3 recombinant antigen

00117-V-01mg Virogen 0,1 mg
EUR 321
Description: HCV NS3 recombinant antigen a.a 1400 to a.a 1643 of HCV polyprotein 22 kDa

HCV NS3 recombinant antigen

00117-V-1000ug Virogen 1000 ug
EUR 1539
Description: HCV NS3 recombinant antigen a.a 1400 to a.a 1643 of HCV polyprotein 22 kDa

HBV core recombinant antigen

00120-V-01mg Virogen 0,1 mg
EUR 321
Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 183 of HBV core antigen 18 kDa

HBV core recombinant antigen

00120-V-1000ug Virogen 1000 ug
EUR 1539
Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 183 of HBV core antigen 18 kDa

HBV core recombinant antigen, Delta

00121-V-01mg Virogen 0,1 mg
EUR 321
Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 144 of HBV core antigen 16 kDa

HBV core recombinant antigen, Delta

00121-V-1000ug Virogen 1000 ug
EUR 1539
Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 144 of HBV core antigen 16 kDa

HBV surface recombinant antigen HBsAg

00122-V-01mg Virogen 0,1 mg
EUR 321
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant

HBV surface recombinant antigen HBsAg

00122-V-1000ug Virogen 1000 ug
EUR 1539
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant

HBV surface recombinant antigen HBsAg antigen

00123-V-01mg Virogen 0,1 mg
EUR 321
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant High purity

HBV surface recombinant antigen HBsAg antigen

00123-V-1000ug Virogen 1000 ug
EUR 1539
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant High purity

HBV surface recombinant antigen HBsAg antigen

00124-V-01mg Virogen 0,1 mg
EUR 321
Description: HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant

HBV surface recombinant antigen HBsAg antigen

00124-V-1000ug Virogen 1000 ug
EUR 1539
Description: HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant

HEV (Birma) ORF2 recombinant antigen

00131-V-01mg Virogen 0,1 mg
EUR 321
Description: HEV (Birma) ORF2 recombinant antigen a.a. 633 to a.a 659.

HEV (Birma) ORF2 recombinant antigen

00131-V-1000ug Virogen 1000 ug
EUR 1539
Description: HEV (Birma) ORF2 recombinant antigen a.a. 633 to a.a 659.

HEV (Birma) ORF2 recombinant antigen

00132-V-01mg Virogen 0,1 mg
EUR 321
Description: HEV (Birma) ORF2 recombinant antigen a.a. 403 to a.a 461.

HEV (Birma) ORF2 recombinant antigen

00132-V-1000ug Virogen 1000 ug
EUR 1539
Description: HEV (Birma) ORF2 recombinant antigen a.a. 403 to a.a 461.

AA 403-461 HEV Birma ORF2 Recombinant Antigen

00133-V-01mg Virogen 0,1 mg
EUR 321
Description: HEV (Birma) ORF2 recombinant antigen a.a. 92 to a.a 123.

AA 403-461 HEV Birma ORF2 Recombinant Antigen

00133-V-1000ug Virogen 1000 ug
EUR 1539
Description: HEV (Birma) ORF2 recombinant antigen a.a. 92 to a.a 123.

T, Pallidum recombinant antigen p15

00141-V-01mg Virogen 0,1 mg
EUR 321
Description: T. Pallidum recombinant antigen p15 (full length)

T, Pallidum recombinant antigen p15

00141-V-1000ug Virogen 1000 ug
EUR 1539
Description: T. Pallidum recombinant antigen p15 (full length)

T, Pallidum recombinant antigen p17

00142-V-01mg Virogen 0,1 mg
EUR 321
Description: T. Pallidum recombinant antigen p17 (full length)

T, Pallidum recombinant antigen p17

00142-V-1000ug Virogen 1000 ug
EUR 1539
Description: T. Pallidum recombinant antigen p17 (full length)

T, Pallidum recombinant antigen p45

00143-V-01mg Virogen 0,1 mg
EUR 321
Description: T. Pallidum recombinant antigen p45 (full length)

T, Pallidum recombinant antigen p45

00143-V-1000ug Virogen 1000 ug
EUR 1539
Description: T. Pallidum recombinant antigen p45 (full length)

T, pallidum recombinant antigen TmpA

00144-V-01mg Virogen 0,1 mg
EUR 321
Description: T. Pallidum recombinant antigen TmpA (full length)

T, pallidum recombinant antigen TmpA

00144-V-1000ug Virogen 1000 ug
EUR 1539
Description: T. Pallidum recombinant antigen TmpA (full length)

HCV core 2-119aa recombinant antigen

00150-V-01mg Virogen 0,1 mg
EUR 321
Description: HCV core 2-119aa recombinant antigen. Genotypes available: 1a, 1b, 2a, 2b, 3a, 3b, 3/10, 4, 5, 6a

HCV core 2-119aa recombinant antigen

00150-V-1000ug Virogen 1000 ug
EUR 1539
Description: HCV core 2-119aa recombinant antigen. Genotypes available: 1a, 1b, 2a, 2b, 3a, 3b, 3/10, 4, 5, 6a

HCV Core 24 Antigen

00151-V-01mg Virogen 0,1 mg
EUR 321
Description: HCV core 24 antigen.

HCV Core 24 Antigen

00151-V-1000ug Virogen 1000 ug
EUR 1539
Description: HCV core 24 antigen.

HCV core recombinant antigen

00152-V-01mg Virogen 0,1 mg
EUR 321
Description: HCV core recombinant antigen a.a.105-302

HCV core recombinant antigen

00152-V-1000ug Virogen 1000 ug
EUR 1539
Description: HCV core recombinant antigen a.a.105-302

HCV NS3 1192-1456 aa Recombinant Antigen

00153-V-01mg Virogen 0,1 mg
EUR 321
Description: HCV NS3 1192-1456aa recombinant antigen a.a.1192-1459. Available genotypes: 1a, 1b, 2b, 2c, 5, 6a

HCV NS3 1192-1456 aa Recombinant Antigen

00153-V-1000ug Virogen 1000 ug
EUR 1539
Description: HCV NS3 1192-1456aa recombinant antigen a.a.1192-1459. Available genotypes: 1a, 1b, 2b, 2c, 5, 6a

HCV NS3 1359-1456aa antigen

00154-V-01mg Virogen 0,1 mg
EUR 321
Description: HCV NS3 1359-1456aa antigen. The protein contains immunodominant regions (1359-1456aa). available genotypes: 1a, 1b, 2b, 3, 4, 5, 6

HCV NS3 1359-1456aa antigen

00154-V-1000ug Virogen 1000 ug
EUR 1539
Description: HCV NS3 1359-1456aa antigen. The protein contains immunodominant regions (1359-1456aa). available genotypes: 1a, 1b, 2b, 3, 4, 5, 6

HCV NS4 mosaic recombinant antigen

00155-V-01mg Virogen 0,1 mg
EUR 321
Description: HCV NS4 mosaic recombinant antigen a.a1691-1710, 1712-1733, 1921-1940. Genotypes available: 1, 2, 3, 5.

HCV NS4 mosaic recombinant antigen

00155-V-1000ug Virogen 1000 ug
EUR 1539
Description: HCV NS4 mosaic recombinant antigen a.a1691-1710, 1712-1733, 1921-1940. Genotypes available: 1, 2, 3, 5.

HCV NS4 1916-1947aa recombinant antigen

00156-V-01mg Virogen 0,1 mg
EUR 321
Description: HCV NS4 1916-1947aa recombinant antigen.

HCV NS4 1916-1947aa recombinant antigen

00156-V-1000ug Virogen 1000 ug
EUR 1539
Description: HCV NS4 1916-1947aa recombinant antigen.
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Amongst these, 215 DEGs had been upregulated and 242 DEGs had been downregulated within the acute injured samples in contrast with unhurt samples. The GO enrichment evaluation indicated that these DEGs had been primarily concerned in transport, the oxidation-reduction course of, the metabolic course of, steel ion binding, hydrolase exercise, and oxidoreductase exercise. The KEGG evaluation revealed that these DEGs had been considerably enriched within the PI3K-Akt signaling pathway, protein digestion and absorption pathway, and focal adhesion pathway. The hub genes together with Hnf4α, Pck1 and Timp1 had been validated by the qRT-PCR assay in NRK-49F cells within the H/R mannequin.

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Categories

  • Blog
  • precipitation
  • Premix
  • Preps
  • primers
  • reverse
  • RIA

Recent Posts

  • PolymorphPrep
  • Capilia TB-Neo
  • Rabies Ag Test Kit
  • Bakkenolide‑IIIa ameliorates lipopolysaccharide‑induced inflammatory injury in human umbilical vein endothelial cells by upregulating LINC00294
  • Human Inflammatory Neutrophils Express Genes Encoding Peptidase Inhibitors: Production of Elafin Mediated by NF-κB and CCAAT/Enhancer-Binding Protein β
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