fluoresence microscopy neurons

Publications


2010
Lavebratt, C., Sjoholm, L., Soronen, P., Paunio, T., Vawter, M., Bunney, W., Adolfsson, R., Forsell, Y., Wu, J., Kelsoe, J., Partonen, T., Shalling, M., (2010). CRY2 is Associated with Depression. PLos ONE 5(2).
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2009
Martin, M.V., Rollins, B. Sequeira, P.A., Mesen, A., Byerley, W., Stein, R., Moon, E.A., Akil, H., Jones, E.G., Watson, S.J., Barchas, J., Delisi, L.E., Myers, R.M., Schatzberg, A., Bunney, W.E., Vawter, M.P. (2009). Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation. BMC Med Genomics 2(1):62.
PubMed | PDF | Supplementary Data

Sequeira A, Mamdani F, Ernst C, Vawter MP, Bunney WE, Lebel V, Rehal S, Klempan T, Gratton A, Benkelfat C, Rouleau GA, Mechawar N, Turecki G. (2009). Global Brain Gene Expression Analysis Links Glutamatergic and GABAergic Alterations to Suicide and Major Depression. PLoS ONE 4(8):e6585.
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Rollins B, Martin MV, Sequeira PA, Moon EA, Morgan LZ, Watson SJ, Schatzberg A, Akil H, Myers RM, Jones EG, Wallace DC, Bunney WE, Vawter MP. (2009). Mitochondrial Variants in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder. PLoS ONE 4(3): e4913. doi:10.1371/journal.pone.0004913.
PubMed | PDF | Published Comments

Bertisch, H., Mesen-Fainardi, A., Martin, M.V., Pérez-Vargas, V., Vargas-Rodríguez, T., Delgado, G., Delgado, C., Llach, M., LaPrade, B., Byerley, W., Bunney, W.E., Vawter, M.P., DeLisi, L.E.; Pritzker Neuropsychiatric Research Consortium. (2009) Neuropsychological performance as endophenotypes in extended schizophrenia families from the Central Valley of Costa Rica. Psychiatr Genet. Feb;19(1):45-52.
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Altar, C.A., Vawter, M.P., Ginsberg, S.D. (2009) Target Identification for CNS Diseases by Transcriptional Profiling. Neuropsychopharmacology. Jan;34(1):18-54.
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2008
Shao, L., Martin, M.V., Watson, S.J., Schatzberg, A., Akil, H., Myers, R.M., Jones, E.G., Bunney, W.E., Vawter, M.P. (2008). Mitochondrial involvement in psychiatric disorders. Ann Med. 40(4):281-95. Review.
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Sequeira, A., Meng, F., Rollins, B., Myers, R.M., Jones, E.G., Watson, S.J., Akil, H., Schatzberg, A.F., Barchas, J., Bunney, W.E., Vawter, M.P. (2008). Coding SNPs included in exon arrays for the study of psychiatric disorders. Mol Psychiatry. 13(4):363-5.
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Shao, L., Vawter, M.P. (2008). Shared gene expression alterations in schizophrenia and bipolar disorder. Biol Psychiatry. 64(2):89-97.
PubMed | PDF | Tables 1-6 | Figure 1 | Coefficient Table


2007
Li, J.Z., Meng, F., Tsavaler, L., Evans, S.J., Choudary, P.V., Tomita, H., Vawter, M.P., Walsh, D., Shokoohi, V., Chung, T., Bunney, W.E., Jones, E.G., Akil, H., Watson, S.J., Myers, R.M. (2007). Sample matching by inferred agonal stress in gene expression analyses of the brain. 24(8):336.
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Atz, M.E., Walsh, D., Cartagena, P., Li, J., Evans, S., Choudary, P., Overman, K., Stein, R., Tomita, H., Potkin, S.G., Myers, R.M., Watson, S.J. Jones, E.G., Akil, H., Bunney, Jr., W.E., Vawter, M.P. (2007). Methodological considerations for gene expression profiling of human brain. J Neurosci Methods. 163(2):295-309.
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Vawter, M.P., Harvey, P.D., DeLisi, L.E. (2007). Dysregulation of X-linked gene expression in Klinefelter's Syndrome and association with verbal cognition. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. Mar 8.
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Atz, M.E., Rollins, B., Vawter, M.P. (2007). Association of bipolar disorder with NCAM1 polymorphisms and alternatively spliced isoforms. Psychiatric Genetics. April, 17(2): 55-67.
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2006
Vawter, M.P., Atz, M.E., Rollins, B., Shao, L., Cooper-Casey, K.M., Byerley, W.F. (2006). Genome scans and gene expression microarrays: converging approaches to identify candidate genes and regulatory loci in schizophrenia. Human Genetics. 119(5):558-70.
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Vawter, M.P., Tomita, H., Meng, F., Bolstad, B., Li, J., Evans, S., Choudary, P., Atz, M.E., Shao, L., Neal, C., Walsh, D.M., Speed, T., Myers, R., Jones, E.G., Watson, S.J., Akil, H., Bunney, W.E. Jr. (2006). Mitochondrial related genes are sensitive to agonal-pH state: implications for brain disorders. Mol Psychiatry,11(7):615, 663-79.
PubMed | PDF | Tables 1-14 and Figures 1-3 | Gene List

Karssen, A.M., Li, J.Z., Her, S., Patel, P.D., Meng, F., Evans, S.J., Vawter, M.P., Tomita, H., Choudary, P.V., Bunney, W.E., Jones, E.G., Watson, S.J., Akil, H., Myers, R.M., Schatzberg, A.F., Lyons, D.M. (2006). Application of microarray technology in primate behavioral neuroscience research. Methods, 38, 227-234.
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2005
Choudary, P.V., Molnar, M., Evans, S.J., Tomita, H., Li, J.Z.,Vawter, M.P., Myers, R.M., Bunney, W.E., Akil, H., Watson, S.J., Jones, E.G. (2005). Altered cortical glutamate and GABA signaling and glial cell involvement in major depression. Proceedings National Academy Science, 102(43), 15653-8.
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2004
Vawter, M.P. , Ferran, E., Galke, B., Cooper, K.C., Bunney, W.E., Byerley, W. (2004). Microarray screening of lymphocyte gene expression differences in a multiplex schizophrenia pedigree. Schizophrenia Research 67(1):41-52.
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Evans, S.J., Choudary, P.V., Neal, C.R., Li, J.Z., Vawter, M.P., Tomita, H., Lopez, J.F., Thompson, R.C., Meng, F., Stead, J.D., Walsh, D.M., Myers, R.M., Bunney, W.E., Watson, S.J., Jones, E.G., Akil, H. (2004). Dysregulation of the fibroblast growth factor system in major depression. Proceedings National Academy Science, 101(43):15506-11.
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Li, J.Z., Vawter, M.P., Walsh, D.M., Tomita, H., Evans, S.J., Choudary, P.V., Lopez, J.F., Avelar,A., Shokoohi, V., Chung, T., Mesarwi, O., Jones, E.G., Watson, S.J., Akil, H., Bunney, W.E., Myers, R.M. (2004). Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions. Human Molecular Genetics, 13(6):609-16.
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Tomita*,H., Vawter*, M.P., Walsh*, D.M., Evans, S.J., Choudary, P.V., Li, J., Overman, K.M., Atz, M. E. , Myers, R.M., Jones E. G., Watson, S.J., Akil, H., Bunney, W.E. Jr. (2004). Postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain. Biological Psychiatry 55(4), 346-352. *Authors contributed equally to the work.
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*Vawter, M.P., *Evans, S.J., *Choudary, P.V., *Tomita, H., Meador-Woodruff, J.H., Molnar, M., Lopez J.F., Li J., Myers R.M., Akil H., Watson S.J., Jones E.G., Bunney W.E. (2004). Gender specific gene expression in postmortem human brain: localization to sex chromosomes. Neuropsychopharmacology,29(2):373-84.*Authors contributed equally to the work.
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Vawter, M.P., Shannon Weickert, C., Ferran, E., Matsumoto, M.,Overman, K., Hyde, T.M., Weinberger, D.R., Bunney, W.E., Kleinman, J.E. (2004). Gene expression of metabolic enzymes and a protease inhibitor in the prefrontal cortex are decreased in schizophrenia. Neurochem Res. 29 (6): 1245-1255.
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2003
*Evans, S.J., *Choudary, P.V., *Vawter M.P., Li J., Meador-Woodruff, J.H., Lopez, J.F., Burke, S.M., Thompson, R.C., Myers, R.M., Jones, E.G., Bunney, W.E., Watson, S.J., and Akil, H. (2003). DNA microarray analysis of functionally discrete human brain regions reveals divergent transcriptional profiles. Neurobiology of Disease 14, 240-250. *Authors contributed equally to the work.
PubMed | PDF Bunney, W.E., Bunney, B.G., Vawter, M.P., Tomita, H., Li, J., Evans, S.J., Choudray, P., Myers, R.M., Jones, E.G., Watson, S.J., Akil, H. (2003). Microarray technology: a review of new strategies to discover candidate vulnerability genes in psychiatric disorders. American Journal of Psychiatry, 160 (4), 657-666.
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Comi, A.M., Hunt, P., Vawter, M.P., Pardo, C.A., Becker, K.G., Pevsner, J. (2003). Increased fibronectin expression in sturge-weber syndrome fibroblasts and brain tissue. Pediatr Res. 53(5):762-9.
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Lehrmann, E., Oyler, J., Vawter, M.P., Hyde, T.M., Kolachana, B., Kleinman, J.E., Huestis, M.A., Becker, K.G., Freed, W.J. (2003). Transcriptional profiling in the human prefrontal cortex: evidence for two activational states associated with cocaine abuse. Pharmacogenomics J. 3(1):27-40.
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Thompson, P.M., Egbufoama, S., Vawter, M.P. (2003). SNAP-25 reduction in the hippocampus of patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 27(3):411-7.
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Cheadle, C., Vawter, M.P., Freed, W.J., Becker, K.G. (2003). Analysis of microarray data using Z score transformation. J Mol Diagn. 5(2):73-81.
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Lehrmann, E., Hyde, T.M., Vawter, M.P., Becker, K.G., Kleinman, J.E., Freed, W.J. (2003). The use of microarrays to characterize neuropsychiatric disorders: postmortem studies of substance abuse and schizophrenia. Curr Mol Med. 3(5):437-46.
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Blaabjerg, M., Baskys, A., Zimmer, J., Vawter, M.P. (2003). Changes in hippocampal gene expression after neuroprotective activation of group I metabotropic glutamate receptors. Brain Res Mol Brain Res. 117(2):196-205.
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2002
Truckenmiller, M.E., Vawter, M.P., Zhang P., Conejero-Goldberg, C., Dillon-Carter, O., Morales, N., Cheadle, C., Becker, K.G., Freed, W.J. (2002). AF5, a CNS cell line immortalized with an N-terminal fragment of SV40 large T: growth, differentiation, genetic stability, and gene expression. Exp Neurol. Jun;175(2):318-37.
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Vawter, M.P., Thatcher, L., Usen, N., Hyde, T.M., Kleinman, J.E., Freed, W.J. (2002). Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia. Mol Psychiatry. 7(6):571-8.
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Vawter, M.P., Crook, J.M., Hyde, T.M., Kleinman, J.E., Weinberger, D.R., Becker, K.G., Freed, W.J. (2002). Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study.Schizophr Res. 58(1):11-20.
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2001
Konu, O., Kane, J.K., Barrett, T., Vawter, M.P., Chang, R., Ma, J.Z., Donovan, D.M., Sharp, B., Becker, K.G., Li, M.D. (2001). Region-specific transcriptional response to chronic nicotine in rat brain. Brain Res. 909(1-2):194-203.
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Vawter, M.P., Barrett, T., Cheadle, C., Sokolov, B.P., Wood, W.H. 3rd, Donovan, D.M., Webster,M., Freed, W.J., Becker, K.G. (2001). Application of cDNA microarrays to examine gene expression differences in schizophrenia. Brain Res Bull. Jul 15;55(5):641-50.
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Barrett, T., Xie, T., Piao, Y., Dillon-Carter, O., Kargul, G.J., Lim, M.K., Chrest, F.J., Wersto, R., Rowley, D.L., Juhaszova, M., Zhou, L., Vawter, M.P., Becker, K.G., Cheadle, C., Wood, W.H. 3rd, McCann, U.D., Freed, W.J., Ko, M.S., Ricaurte, G.A., Donovan, D.M. (2001). A murine dopamine neuron-specific cDNA library and microarray: increased COX1 expression during methamphetamine neurotoxicity. Neurobiol Dis. 8(5):822-33.
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Vawter, M.P., Usen, N., Thatcher, L., Ladenheim, B., Zhang, P., VanderPutten, D.M., Conant, K., Herman, M.M., van Kammen, D.P., Sedvall, G., Garver, D.L., Freed, W.J. (2001). Characterization of human cleaved N-CAM and association with schizophrenia. Exp Neurol. 172(1):29-46.
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Freed, W.J., Vawter, M.P. (2001). Microarrays: applications in neuroscience to disease, development, and repair. Restor Neurol Neurosci. 18(2-3):53-6.
PubMed

Truckenmiller, M.E., Vawter, M.P., Cheadle, C., Coggiano, M., Donovan, D.M., Freed, W.J., Becker, K.G. (2001). Gene expression profile in early stage of retinoic acid-induced differentiation of human SH-SY5Y neuroblastoma cells. Restor Neurol Neurosci. 18(2-3):67-80.
PubMed

Barrett, T., Cheadle, C., Wood, W.B., Teichberg, D., Donovan, D.M., Freed, W.J., Becker, K.G., Vawter, M.P. (2001). Assembly and use of a broadly applicable neural cDNA microarray. Restor Neurol Neurosci. 18(2-3):127-35.
PubMed

Collaborations


Willour VL, Chen H, Toolan J, Belmonte P, Cutler DJ, Goes FS, Zandi PP, Lee RS, MacKinnon DF, Mondimore FM, Schweizer B; Bipolar Disorder Phenome Group; NIMH Genetics Initiative Bipolar Disorder Consortium, DePaulo JR Jr, Gershon ES, McMahon FJ, Potash JB. Collaborators: McMahon F, Steele J, Pearl J, Kassem L, Lopez V, Potash J, MacKinnon D, Miller E, Toolan J, Zandi P, Schulze T, Nwulia E, Simpson S, Nurnberger J, Miller M, Bowman E, Reich T, Goate A, Rice J, DePaulo JR Jr, Simpson S, Stine C, Gershon E, Kazuba D, Maxwell E, Nurnberger J, Miller MJ, Bowman ES, Rau NL, Moe PR, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Foroud T, Flury L, Dick DM, Edenberg H, Rice J, Reich T, Goate A, Bierut L, McInnis M, DePaulo JR Jr, MacKinnon DF, Mondimore FM, Potash JB, Zandi PP, Avramopoulos D, Payne J, Berrettini W, Byerley W, Vawter M, Coryell W, Crowe R, Gershon E, Badner J, McMahon F, Liu C, Sanders A, Caserta M, Dinwiddie S, Nguyen T, Harakal D, Kelsoe J, McKinney R, Scheftner W, Kravitz HM, Marta D, Vaughn-Brown A, Bederow L, McMahon FJ, Kassem L, Detera-Wadleigh S, Austin L, Murphy DL. (2009). Family-based association of FKBP5 in bipolar disorder. Mol Psychiatry. 14(3):261-8.
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Payne JL, Klein SR, Zamoiski RB, Zandi PP, Bienvenu OJ, Mackinnon DF, Mondimore FM, Schweizer B, Swartz KL; NIMH Genetics Initiative Bipolar Disorder Consortium, Crowe RP, Scheftner WA, Weissman MM, Levinson DF, DePaulo JR Jr, Potash JB. Collaborators: Nurnberger J, Miller MJ, Bowman ES, Rau NL, Moe PR Jr, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Foroud T, Flury L, Dick DM, Edenberg H, Rice J, Reich T, Goate A, Bierut L, McInnis M, DePaulo JR Jr, MacKinnon DF, Mondimore FM, Potash JB, Zandi PP, Avramopoulos D, Payne J, Berrettini W, Byerley W, Vawter M, Coryell W, Crowe R, Gershon E, Badner J, McMahon F, Liu C, Sanders A, Caserta M, Dinwiddie S, Nguyen T, Harakal D, Kelsoe J, McKinney R, Scheftner W, Kravitz HM, Marta D, Vaughn-Brown A, Bederow L, McMahon FJ, Kassem L, Detera-Wadleigh S, Austin L, Murphy DL. (2009). Premenstrual mood symptoms: study of familiality and personality correlates in mood disorder pedigrees. Arch Womens Ment Health. 12(1):27-34.
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Zandi, P.P., Belmonte, P.L., Willour, V.L., Goes, F.S., Badner, J.A., Simpson, S.G., Gershon, E.S., McMahon, F.J., DePaulo, J.R. Jr, Potash, J.B.; Bipolar Disorder Phenome Group; National Institute of Mental Health Genetics Initiative Bipolar Disorder Consortium. Collaborators: Nurnberger, Miller MJ, Bowman ES, Reich T, Goate , Rice , DePaulo , Simpson , Stine C, Gershon , Kazuba D, Maxwell E, Miller , Bowman , Rau NL, Moe PR, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Foroud T, Flury L, Dick DM, Edenberg H, Rice , Reich , Goate , Bierut L, McInnis M, DePaulo , MacKinnon DF, Mondimore FM, Potash , Zandi , Avramopoulos D, Payne J, Berrettini W, Byerley , Vawter M, Coryell , Crowe R, Gershon , Badner , McMahon , Liu C, Sanders A, Caserta M, Dinwiddie S, Nguyen T, Harakal D, Kelsoe , McKinney R, Scheftner W, Kravitz HM, Marta D, Vaughn-Brown A, Bederow L, McMahon , Kassem L, Detera-Wadleigh S, Austin S, Murphy DL. (2008). Association study of Wnt signaling pathway genes in bipolar disorder. Arch Gen Psychiatry. 65(7):785-93.
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Sklar P, Smoller JW, Fan J, Ferreira MA, Perlis RH, Chambert K, Nimgaonkar VL, McQueen MB, Faraone SV, Kirby A, de Bakker PI, Ogdie MN, Thase ME, Sachs GS, Todd-Brown K, Gabriel SB, Sougnez C, Gates C, Blumenstiel B, Defelice M, Ardlie KG, Franklin J, Muir WJ, McGhee KA, MacIntyre DJ, McLean A, VanBeck M, McQuillin A, Bass NJ, Robinson M, Lawrence J, Anjorin A, Curtis D, Scolnick EM, Daly MJ, Blackwood DH, Gurling HM, Purcell SM. Collaborators: Marangell LB, Calabrese JR, Nierenberg AA, Hauser P, Ketter TA, Thomas M, Patel J, Fossey MD, Gyulai L, Thase ME, Bowden CL, Molay F, Rosen-Sheidley B, Silfies L, Gejman PV, Sanders AR, Amin F, Buccola N, Byerley W, Cloninger CR, Crowe R, Black D, Freedman R, Levinson D, Mowry B, Silverman J, Nurnberger J, Miller MJ, Bowman ES, Rau NL, Moe PR, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Foroud T, Flury L, Dick DM, Edenberg H, Rice J, Reich T, Goate A, Bierut L, McInnis M, DePaulo JR Jr, MacKinnon DF, Mondimore FM, Potash JB, Zandi PP, Avramopoulos D, Payne J, Berrettini W, Byerley W, Vawter M, Coryell W, Crowe R, Gershon E, Badner J, McMahon F, Liu C, Sanders A, Caserta M, Dinwiddie S, Nguyen T, Harakal D, Kelsoe J, McKinney R, Scheftner W, Kravitz HM, Marta D, Vaughn-Brown A, Bederow L, McMahon FJ, Kassem L, Detera-Wadleigh S, Austin L, Murphy DL. (2008). Whole-genome association study of bipolar disorder. Mol Psychiatry Jun;13(6):558-69.
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